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Wednesday, March 28, 2018

Genome does not like to excessively change in male germ cells

https://ift.tt/eA8V8J Researchers report the function of GTSF1 in germ cells. The study shows that GTSF1 is an essential factor for secondary piRNA biogenesis probably through the step where PIWI-piRNA complexes grasp and/or stabilize the target RNA. The discovery gives important insights on how male germ cells avoid the genome instability caused by excessive retrotransposition.

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