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Monday, October 30, 2017

Driving drug resistance out of fungi

http://ift.tt/eA8V8J Scientists have developed a CRISPR-Cas9-based 'gene drive' platform to create diploid strains of the pathogen in which both gene copies could be efficiently deleted. The technique may lead the way toward a better understanding of drug resistance and biofilm-forming mechanisms, and through future research, it could help pinpoint new drug targets and combination therapies.

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