Basis of development of vertebrate limb muscles has been established in cartilaginous fishes

http://ift.tt/eA8V8J Scientists have discovered that both bony and cartilaginous fish develop their appendages via a shared mechanism -- the mechanism is also observed in land-dwelling vertebrates such as mice. They found the fin muscles of cartilaginous are formed by muscle precursors expressing Lbx1 expression, a gene that coordinates limb-muscle formation. This work revisits some related evolutionary hypotheses using a molecular biology approach and provides new insights.

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