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Tuesday, September 19, 2017

Treatment-resistant melanoma may be vulnerable to a drug holiday, study finds

http://ift.tt/eA8V8J A new study has uncovered the mechanisms by which treatment-resistant melanoma become vulnerable to cessation of a class of drugs called MAP kinase (MAPK)-targeted inhibitors. By identifying these mechanisms, the scientists discovered that therapeutic benefits for patients could derive from a one-two punch of a drug holiday of MAPK inhibitors followed by a class of drugs called DNA repair inhibitors.

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