First-in-human clinical trial of new targeted therapy drug reports promising responses for multiple cancers

https://ift.tt/eA8V8J A phase I, first-in-human study reveals for the first time, an investigational drug that is effective and safe for patients with cancers caused by an alteration in the receptor tyrosine kinase known as RET. The drug appears to be promising as a potential therapy for RET-driven cancers, such as medullary and papillary thyroid, non-small cell lung, colorectal and bile duct cancers, which have been historically difficult to treat.

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Fecal microbiota transplantation produces sustained improvements in cognitive and clinical outcomes

https://ift.tt/eA8V8J Long-term results of a randomized study demonstrate sustained improvements in hepatic encephalopathy episodes, hospitalizations, and cognitive performance compared with standard-of-care.

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A heavyweight solution for lighter-weight combat vehicles

https://ift.tt/eA8V8J Researchers have developed and successfully tested a novel process -- called Friction Stir Dovetailing -- that joins thick plates of aluminum to steel. The new process will be used to make lighter-weight military vehicles that are more agile and fuel efficient.

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Pulsed corona discharge removes pharmaceutical residues from wastewater

https://ift.tt/eA8V8J New research examines the removal of harmful organic substances, such as pharmaceutical residues, energy efficiently from wastewater using only electricity. According to practical tests, pulsed corona discharge (PCD) may significantly reduce the environmental burden of pharmaceutical residues.

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'Molecular microscope' system safer, more effective in heart and lung transplant biopsies

https://ift.tt/eA8V8J A transplant biopsy system that uses gene chips to read molecules is far safer and more effective than existing approaches used for heart transplant biopsies and is showing promising results for lung transplant biopsies, new research shows.

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Temperature affects insecticide efficacy against malaria vectors

https://ift.tt/eA8V8J Ambient temperature has a marked effect on the toxicity of the most commonly used insecticides for malaria control, according to a new study. The results underline the need to evaluate the efficacy of these chemicals under real field conditions.

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When superconductivity disappears in the core of a quantum tube

https://ift.tt/eA8V8J Predicting the behavior of electrons in a material is not easily done. Physicists have replaced the electrons with ultra-cold neutral lithium atoms that they had circulated in a one-dimensional quantum tube. The scientists were able to confirm an unusual state of matter that retains its insulation regardless of the level of attraction between the particles. This work opens the way to new materials with atypical properties.

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